2-Phenylacetamide, CAS No. 103-81-1

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103-81-1

Catalog No. EBD25701

CAS 103-81-1

Name 2-Phenylacetamide

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Basic Information

Synonyms: 2-Phenylacetamide alpha-toluamide alpha-phenylacetamide phenylacetamide 2-phenyl-acetamid acetamide,2-phenyl- alpha-toluimidicacid benzeneacetamide 2-Phenyl-acetamide

Molecular Formula: C8H9NO

Molecular Weight: 135.16

MDL Number: MFCD00059193

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Other Pharmaceutical Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

2-Phenylacetamide is an organic compound with the molecular formula C8H9NO. It is a white crystalline solid derived from phenylacetic acid. Structurally, it consists of a phenyl group attached to an acetamide moiety, making it a simple aromatic amide. This compound serves as a versatile intermediate in organic synthesis and pharmaceutical manufacturing. Its primary application is as a key building block in the synthesis of various pharmaceuticals, including penicillin G and other β-lactam antibiotics. It is also used in the production of other drugs and fine chemicals. The amide group can be hydrolyzed to yield phenylacetic acid or undergo other transformations. 2-Phenylacetamide is considered a relatively stable compound under normal conditions. It should be handled with standard laboratory precautions, avoiding inhalation of dust and contact with skin and eyes.

Physical Properties

Melting Point: 156 °C

Boiling Point: 280-290 °C (dec.)

Flash Point: 142.6 °C

Density: 1.098 g/cm3