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    1169748-84-8

    Catalog No. EBD1616110

    CAS 1169748-84-8

    Name 5-aminopyridin-3-ylboronic acid

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    Basic Information

    Synonyms: 5-aminopyridin-3-ylboronicacid Boronicacid,B-(5-amino-3-pyridinyl)-

    Molecular Formula: C5H7BN2O2

    Molecular Weight: 137.93

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters

    Product Description:
    5-Aminopyridin-3-ylboronic acid is an aromatic heterocyclic boronic acid derivative featuring both an amino group and a boronic acid group on a pyridine ring. This bifunctional structure makes it a versatile building block in organic synthesis, particularly valuable for Suzuki-Miyaura cross-coupling reactions, where the boronic acid moiety acts as a key coupling partner. Its primary and most significant application is in pharmaceutical research and development as a crucial intermediate for constructing complex drug-like molecules. The 5-amino-3-pyridinyl scaffold is a privileged structure found in numerous bioactive compounds and active pharmaceutical ingredients (APIs) targeting various diseases. It is extensively used to synthesize kinase inhibitors, receptor antagonists, and other therapeutic agents. As a commercially available synthon, it facilitates the efficient introduction of the aminopyridine moiety into larger molecular architectures. Handling requires standard precautions for boronic acids and amines, including protection from moisture and use in inert atmospheres to preserve reactivity.
    Physical Properties
    mg g kg ml l t