2-Aminopyrimidine-5-carbaldehyde, CAS No. 120747-84-4

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120747-84-4

Catalog No. EBD937839

CAS 120747-84-4

Name 2-Aminopyrimidine-5-carbaldehyde

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Basic Information

Synonyms: 2-Aminopyrimidine-5-carbaldehyde 2-Amino-5-pyrimidinecarboxyaldehyde ASISCHEMC63547 2-AMINO-PYRIMIDINE-5-CARBALDEHYDE 5-Pyrimidinecarboxaldehyde,2-amino- 5-Pyrimidinecarboxaldehyde,2-amino-(9CI) 2-Amino-5-pyrimidinecarbaldehyde 2-Amino-pyrimidine-5-carbaldehyde,97%

Molecular Formula: C5H5N3O

Molecular Weight: 123.11

MDL Number: MFCD03701714

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

2-Amino-5-pyrimidinecarboxaldehyde is a heterocyclic organic compound featuring both an amino group and an aldehyde group on a pyrimidine ring. This bifunctional structure makes it a versatile and valuable building block in organic synthesis. Its primary application is as a key pharmaceutical intermediate. The pyrimidine core is a privileged scaffold in medicinal chemistry, and this specific derivative is widely used in the synthesis of various biologically active molecules. It serves as a crucial precursor for the development of kinase inhibitors, antiviral agents, and other therapeutic compounds targeting diverse disease pathways. The reactive aldehyde group allows for facile condensation reactions, while the amino group can participate in further functionalization or act as a hydrogen bond donor/acceptor in the final drug molecule. Beyond its pharmaceutical applications, it is also employed as a specialized organic synthesis building block in academic and industrial research for constructing complex heterocyclic systems.

Physical Properties

Melting Point: 209-214 °C

Boiling Point: 372.651 °C at 760 mmHg

Flash Point: 179.173 °C

Density: 1.371 g/cm3