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    124668-45-7

    Catalog No. EBD24131

    CAS 124668-45-7

    Name Azetidine-3-carboxamide hydrochloride

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    Basic Information

    Synonyms: Azetidine-3-carboxamidehydrochloride 3-AzetidinecarboxamideHCl

    Molecular Formula: C4H9ClN2O

    Molecular Weight: 136.58

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    3-Azetidinecarboxamide hydrochloride is a heterocyclic organic compound featuring a four-membered azetidine ring with a primary amide functional group, supplied as its hydrochloride salt. This structural motif makes it a valuable and versatile building block in medicinal chemistry. Its primary application is as a key intermediate in the synthesis of various pharmaceutical agents. The strained azetidine ring is of significant interest for its role in modulating the physicochemical and pharmacokinetic properties of drug candidates. This compound is notably utilized in the research and development of protease inhibitors and other bioactive molecules where the incorporation of a small, polar, and conformationally constrained ring system is desired. As a bifunctional synthon containing both a reactive secondary amine (after deprotection or salt cleavage) and a carboxamide group, it serves as a crucial precursor for constructing more complex molecular architectures. Its use is documented in patent literature related to the preparation of therapeutic compounds targeting various diseases.
    Physical Properties
    mg g kg ml l t