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    136866-27-8

    Catalog No. EBD25943

    CAS 136866-27-8

    Name 3,5-Dichloropyrazine-2-carbaldehyde

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    Basic Information

    Synonyms: 3,5-dichloropyrazine-2-carbaldehyde 2-pyrazinecarboxaldehyde,3,5-dichloro- 3,5-dichloro-2-formylpyrazine 3,5-dichloropyrazine-2-carboxaldehyde 3,5-dichloro-2-formylpyrazine,3,5-dichloro-2-formyl-1,4-diazine

    Molecular Formula: C5H2Cl2N2O

    Molecular Weight: 176.99

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    3,5-Dichloro-2-piperazinecarboxaldehyde is a heterocyclic organic compound featuring a piperazine ring substituted with two chlorine atoms and an aldehyde functional group. This specific substitution pattern makes it a valuable and versatile building block in medicinal chemistry. Its primary application is as a key synthetic intermediate in the development of pharmaceutical agents. The compound serves as a crucial precursor in the synthesis of various biologically active molecules, particularly those targeting the central nervous system. For instance, it is a documented intermediate in the synthetic routes for certain antipsychotic drugs and other pharmacologically relevant heterocyclic compounds. The reactive aldehyde group allows for further functionalization, enabling the construction of complex molecular architectures. As a bifunctional molecule containing both an amine (within the piperazine) and an aldehyde, it is also employed in organic synthesis for constructing more complex amine derivatives and heterocyclic systems. Its utility underscores its role in facilitating the discovery and production of new therapeutic candidates.
    Physical Properties

    Boiling Point: 240.75 °C at 760 mmHg

    Flash Point: 99.403 °C

    Density: 1.588 g/cm3

    mg g kg ml l t