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    144584-32-7

    Catalog No. EBD2217465

    CAS 144584-32-7

    Name 3-Bromo-2,4-dichloropyridine

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    Basic Information

    Synonyms: 3-Bromo-2,4-dichloropyridine Pyridine,3-bromo-2,4-dichloro-

    Molecular Formula: C5H2BrCl2N

    Molecular Weight: 226.89

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    2,4-Dichloro-3-bromopyridine is a halogenated pyridine derivative characterized by the presence of chlorine atoms at the 2- and 4-positions and a bromine atom at the 3-position of the pyridine ring. This specific substitution pattern makes it a versatile and valuable synthetic intermediate. Its primary application is in the pharmaceutical industry as a key building block for the synthesis of various active pharmaceutical ingredients (APIs) and complex drug candidates. The halogen atoms serve as reactive handles for sequential cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitutions, allowing for the efficient construction of diverse, functionalized pyridine scaffolds commonly found in medicinal chemistry. As a multi-halogenated heterocycle, it is also a fundamental organic synthesis block used in research and development to create libraries of compounds for biological screening. It is commercially available from suppliers specializing in fine chemicals and pharmaceutical intermediates.
    Physical Properties

    Boiling Point: 254.206 °C at 760 mmHg

    Flash Point: 107.54 °C

    Density: 1.848 g/cm3

    mg g kg ml l t