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    1583-88-6

    Catalog No. EBD14043

    CAS 1583-88-6

    Name 2-(4-fluorophenyl)-ethylamine

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    Basic Information

    Synonyms: 4-fluorophenylethylamine 4-fluorophenethylamine 2-(4-fluoro-phenyl)-ethylamine auroraka-7015 (p-fluorophenyl)ethylamine rarechemalbw0215 p-fluorophenethylamine 4-fluorophenethylamine,99+% 2-(p-fluorophenyl)ethylamine 2-(4-fluorophenyl)-ethylamine 2-(4-fluorophenyl)ethanamine 2-(4-fluorophenyl)ethanaminium 4-Fluoro-benzeneethanamine

    Molecular Formula: C8H10FN

    Molecular Weight: 139.17

    MDL Number: MFCD00134208

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    4-Fluorophenethylamine is an organic compound featuring a phenethylamine backbone with a fluorine substituent at the para position of the aromatic ring. It is a colorless to pale yellow liquid with a molecular formula of C8H10FN. This compound serves as a versatile and important building block in organic synthesis, particularly in medicinal chemistry. Its primary application is as a key intermediate in the synthesis of various pharmaceutical agents. The fluorine atom and the primary amine group make it a valuable precursor for constructing molecules with potential biological activity. It is notably used in the research and development of central nervous system (CNS) active compounds, including potential antidepressants and stimulants, due to its structural similarity to neurotransmitters like dopamine and phenethylamine. As a bifunctional synthon, it is widely employed in amide bond formation, reductive amination, and as a precursor for heterocyclic systems. Its utility extends beyond pharmaceuticals to materials science and agrochemical research. Standard safety precautions for handling amines should be observed, including the use of personal protective equipment due to its potential irritant properties.
    Physical Properties

    Boiling Point: 50-52 °C/0.15 mmHg(lit.)

    Flash Point: 79 °C

    Density: 1.061 g/mL at 25 °C(lit.)

    Refractivity: n20/D 1.5072(lit.)

    Safety Information

    Packing Level: II

    Hazard Category: 6.1(8)

    Transport Codes: 2922

    Analytical Data

    Appearance: clear colorless to slightly yellow liquid

    mg g kg ml l t