L-4-Nitrophenylalanine methyl ester hydrochloride, CAS No. 17193-40-7

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17193-40-7

Catalog No. EBD12127

CAS 17193-40-7

Name L-4-Nitrophenylalanine methyl ester hydrochloride

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Basic Information

Synonyms: H-p-Nitro-Phe-OMeHCl H-Phe(4-NO_2)-OMe.HCl (S)-(+)-4-Nitrophenylalaninemethylesterhydrochloride 4-nitro-l-phenylalaninemethylesterhcl methyl4-nitro-L-phenylalaninatehydrochloride H-Phe(4'-NO2)-OMe·HCl L-4-NitrophenylalanineMethylEsterHydrochloride H-Phe(4-NO2)-OMe·HCl 4-Nitro-L-PhenylalanineMethylEsterHydrochloride (S)-4-Nitrophenylalaninemethylesterhydrochloride

Molecular Formula: C10H13ClN2O4

Molecular Weight: 260.67

MDL Number: MFCD00135754

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

L-4-Nitro-phenylalanine methyl ester hydrochloride is a chiral amino acid derivative. It features a nitro group on the phenyl ring and exists as a hydrochloride salt of the methyl ester. This compound serves as a crucial chiral building block in organic synthesis and pharmaceutical research. Its primary application is as a key intermediate in the synthesis of more complex chiral molecules, particularly in medicinal chemistry. The nitro group can be readily reduced to an amine, allowing for further functionalization. This makes it valuable for constructing peptide mimetics and other bioactive compounds where the L-configuration and aromatic functionality are required. As a protected and activated form of L-4-nitrophenylalanine, it is used in solid-phase peptide synthesis (SPPS) and other coupling reactions. The compound is handled as a fine chemical under standard laboratory safety protocols.

Physical Properties

Melting Point: 210-214 °C

Boiling Point: 360 °C at 760 mmHg

Flash Point: 171.5 °C

Storage: 2-8°C