D(-)-Norvaline, CAS No. 2013-12-9

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2013-12-9

Catalog No. EBD3542

CAS 2013-12-9

Name D(-)-Norvaline

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Basic Information

Synonyms: D-Norvaline D-(-)-2-Aminovalericacid D(-)-Norvaline D(-)-2-Aminovalericacid rarechememwb0167 (r)-2-amino-n-valericacid (r)-(-)-2-aminopentanoicacid (r)-2-aminopentanoicacid h-d-2-aminovalericacid h-d-nva-oh h-d-nhch[ch3(ch2)2]-cooh h-d-norvaline

Molecular Formula: C5H11NO2

Molecular Weight: 117.15

MDL Number: MFCD00008097

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

D-Norvaline is a non-proteinogenic amino acid with the chemical formula C5H11NO2. It is the D-enantiomer of norvaline, an isomer of valine where the side chain is a straight-chain propyl group instead of an isopropyl group. This structural feature makes it a valuable chiral building block in organic synthesis and peptide research. Its primary applications are in the pharmaceutical and life sciences fields. D-Norvaline serves as a key intermediate in the synthesis of various peptide-based drugs and bioactive compounds. It is also used in biochemical research, for instance, as a substrate or inhibitor in studies of enzymes like D-amino acid oxidase (DAAO). Furthermore, it finds utility in the preparation of chiral catalysts and ligands for asymmetric synthesis. As a non-natural amino acid, it is often employed to modulate the pharmacokinetic properties, stability, and biological activity of therapeutic peptides. Its availability in high enantiomeric purity makes it crucial for developing compounds with specific stereochemical requirements.

Physical Properties

Melting Point: >300 °C(lit.)

Boiling Point: 222.9 °C at 760 mmHg

Flash Point: 88.6 °C

Density: 1.067 g/cm3

Solubility: SOLUBLE

Refractivity: -25 ° (C=10, 6mol/L HCl)

Storage: Store at RT.

Analytical Data

Appearance: white to off-white crystals or crystalline powder