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    2051-95-8

    Catalog No. EBD40256

    CAS 2051-95-8

    Name 4-Oxo-4-phenylbutanoic acid

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    Basic Information

    Synonyms: gamma-oxo-benzenebutanoicaci b-benzoylpropionicacid beta-benzoylpropionicacid labotest-bblt00452552 3-benzoylpropionicacid 4-oxo-4-phenylbutyricacid 4-Oxo-4-phenylbutanoicacid

    Molecular Formula: C10H10O3

    Molecular Weight: 178.18

    MDL Number: MFCD00002792

    Categories: Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters Synthetic Chemistry > Basic Synthetic Reagents > C-C Bond Formation Reagents

    Product Description:
    4-Oxo-4-phenylbutanoic acid, also known as 3-benzoylpropionic acid, is a white to off-white crystalline powder with a molecular formula of C10H10O3. It is a bifunctional organic compound featuring both a ketone and a carboxylic acid group, separated by a two-carbon methylene chain. This structure makes it a versatile building block in organic synthesis. Its primary application is as a key synthetic intermediate in the preparation of various heterocyclic compounds, particularly through reactions like the Knorr pyrrole synthesis. It serves as a crucial precursor for the synthesis of substituted pyrroles, which are important scaffolds in medicinal chemistry and materials science. Additionally, it can be used in Michael addition reactions and other carbon-carbon bond-forming transformations to construct more complex molecular architectures. While not a final active pharmaceutical ingredient itself, its derivatives find relevance in research areas related to pharmaceuticals and agrochemicals. It is commercially available from major chemical suppliers for laboratory and potential industrial-scale synthesis. Standard safety precautions for handling organic acids and ketones should be observed.
    Physical Properties

    Melting Point: 114-117 °C(lit.)

    Boiling Point: 359.7 °C at 760 mmHg

    Flash Point: 185.6 °C

    Density: 1.199 g/cm3

    mg g kg ml l t