3-Boc-Aminoazetidine hydrochloride, CAS No. 217806-26-3

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217806-26-3

Catalog No. EBD6571

CAS 217806-26-3

Name 3-Boc-Aminoazetidine hydrochloride

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Basic Information

Synonyms: Tert-butyl azetidin-3-ylcarbamate hydrochloride tert-Butyl(azetidin-3-yl)carbamatehydrochloride tert-butylazetidin-3-ylcarbamatehydrochloride 3-(Boc-amino)azetidineHCl tert-butylN-(azetidin-3-yl)carbamatehydrochloride 3-N-Boc-Aminoazetidinehydrochloride 3-Boc-Aminoazetidinehydrochloride

Molecular Formula: C8H17ClN2O2

Molecular Weight: 208.69

MDL Number: MFCD09839423

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

3-Boc-aminocyclobutane hydrochloride is a chemical compound featuring a cyclobutane ring substituted with a Boc-protected amino group. It is supplied as a hydrochloride salt, which enhances its stability and handling properties. The molecular formula is C9H18N2O2·HCl. This compound is primarily utilized as a key pharmaceutical intermediate. The protected amino group on the nitrogen-containing four-membered ring (azetidine/cyclobutylamine) makes it a valuable building block for the synthesis of more complex molecules, particularly in medicinal chemistry. It is frequently employed in the research and development of drug candidates, where the cyclobutane scaffold is incorporated to modulate the pharmacokinetic and pharmacodynamic properties of the final active pharmaceutical ingredient (API). As a Boc-protected amine, it serves as a versatile synthon in organic synthesis, allowing for selective deprotection and further functionalization under mild acidic conditions. Its application spans across various therapeutic areas, contributing to the construction of novel chemical entities in drug discovery programs.

Physical Properties

Boiling Point: 303 °C at 760 mmHg

Flash Point: 137.1 °C

Safety Information

Packing Level: III

Hazard Category: 9

Transport Codes: 3077