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    230301-11-8

    Catalog No. EBD50730

    CAS 230301-11-8

    Name 5-Boc-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridine

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    Basic Information

    Synonyms: tert-butyl1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate tert-Butyl6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate 5H-Pyrazolo[4,3-c]pyridine-5-carboxylicacid,1,4,6,7-tetrahydro-,1,1-dimethylethylester 5-Boc-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridine

    Molecular Formula: C11H17N3O2

    Molecular Weight: 223.27

    MDL Number: MFCD08059268

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    5-Boc-4,5,6,7-tetrahydropyrazolo[4,3-c]pyridine is a bicyclic heterocyclic compound featuring a fused pyrazole and piperidine ring system. The piperidine nitrogen is protected with a tert-butoxycarbonyl (Boc) group, a common strategy to mask the basic amine functionality during multi-step synthetic sequences. This compound is primarily utilized as a versatile and valuable building block in medicinal chemistry and pharmaceutical research. Its core structure serves as a privileged scaffold for the development of drug candidates targeting various therapeutic areas. The Boc-protected amine allows for selective deprotection and further functionalization, making it a key intermediate in the synthesis of more complex molecules, particularly those intended as active pharmaceutical ingredients (APIs) or their precursors. As a bifunctional molecule containing both a protected amine and a heterocyclic framework, it is a staple in the toolkit of synthetic organic chemists. Its applications extend beyond specific drug programs to general method development for constructing nitrogen-rich heterocycles, which are prevalent in bioactive compounds.
    Physical Properties

    Boiling Point: 387.979 °C at 760 mmHg

    Flash Point: 188.443 °C

    Density: 1.2g/cm3

    mg g kg ml l t