2-Bromobutyryl bromide, CAS No. 26074-52-2

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

26074-52-2

Catalog No. EBD25653

CAS 26074-52-2

Name 2-Bromobutyryl bromide

Get Quote

Basic Information

Synonyms: N,N-Dimethyl-N-2-propenyl-2-propen-1-aminiumchloridehomopolymer 2-Bromobutyrylbromide Bromobutyrylbromide 2-Bromo-n-butyrylbromide 2-bromobutanoylbromide

Molecular Formula: C4H6Br2O

Molecular Weight: 229.9

MDL Number: MFCD00000154

Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Basic Synthetic Reagents > Halogenation Reagents

Product Description:

2-Bromobutyryl bromide is an organic compound with the molecular formula C4H6Br2O. It is a colorless to light yellow liquid with a pungent odor. Structurally, it is an α-bromo acyl bromide, featuring a reactive bromine atom on the alpha carbon and a highly electrophilic acid bromide functional group. This compound is primarily used as a versatile reagent in organic synthesis. Its main application is as a brominating and acylating agent, particularly for introducing the 2-bromobutyryl moiety. It serves as a key building block in the synthesis of various pharmaceuticals and agrochemicals. For instance, it is a crucial intermediate in the production of the anti-inflammatory drug Ibuprofen and its derivatives, where it is used to construct the characteristic α-arylpropionic acid skeleton. Due to its high reactivity, 2-bromobutyryl bromide is moisture-sensitive and reacts violently with water, alcohols, and amines, releasing corrosive hydrogen bromide gas. It must be handled with extreme care under inert atmosphere conditions, using appropriate personal protective equipment.

Physical Properties

Boiling Point: 142-144 °C(lit.)

Flash Point: 110 °C

Density: 1.905 g/mL at 25 °C(lit.)

Refractivity: n20/D 1.512(lit.)

Safety Information

Packing Level: II

Hazard Category: 8

Transport Codes: 3265