6 - Methoxypicolinic acid, CAS No. 26893-73-2

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26893-73-2

Catalog No. EBD17620

CAS 26893-73-2

Name 6 - Methoxypicolinic acid

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Basic Information

Synonyms: 6-Methoxy-pyridine-2-carboxylicacid 6-methoxy-2-pyridinecarboxylicacid 2-pyridinecarboxylicacid,6-methoxy- 6-Methoxypicolinicacid 2-Methoxy-6-picolinicacid 6-methoxypyridine-2-carboxylicacid methyl6-methoxypyridine-2-carboxylate

Molecular Formula: C7H7NO3

Molecular Weight: 153.14

MDL Number: MFCD06800962

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters

Product Description:

2-Methoxypyridine-6-carboxylic acid is an organic compound featuring a pyridine ring substituted with a methoxy group at the 2-position and a carboxylic acid group at the 6-position. It serves as a versatile heterocyclic building block in organic synthesis. Its primary application is in the pharmaceutical industry as a key intermediate for the synthesis of various active pharmaceutical ingredients (APIs). Notably, it is a crucial precursor in the manufacturing of certain non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents that incorporate a functionalized pyridine core. The presence of both the carboxylic acid and methoxy groups allows for further derivatization, making it a valuable synthon for constructing more complex molecular architectures. As a bifunctional molecule, it is also employed in material science research and as a ligand precursor in coordination chemistry. Standard safety precautions for handling carboxylic acids and organic compounds should be observed.

Physical Properties

Melting Point: 38.5-39.5°C

Boiling Point: 300.8 °C at 760 mmHg

Flash Point: 135.7 °C

Density: 1.284 g/cm3