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    30389-17-4

    Catalog No. EBD2557932

    CAS 30389-17-4

    Name 1-METHYL-PROP-2-YNYLAMINE

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    Basic Information

    Synonyms: 1-METHYL-PROP-2-YNYLAMINE but-3-yn-2-amine 3-butyn-2-amine But-3-in-2-amin

    Molecular Formula: C4H7N

    Molecular Weight: 69.11

    Categories: Synthetic Chemistry > Organic Building Blocks > Amines Synthetic Chemistry > Basic Synthetic Reagents > Other Basic Synthetic Reagents

    Product Description:
    1-Methyl-2-propynylamine, also known as propargylamine, N-methyl, is an organic compound with the molecular formula C4H7N. It is a colorless to pale yellow liquid with a strong, unpleasant odor. The molecule features both a primary amine group and a terminal alkyne group, making it a versatile bifunctional building block in organic synthesis. Its primary application is as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. The amine and alkyne functionalities allow for diverse chemical transformations, including nucleophilic substitution, condensation reactions, and metal-catalyzed coupling reactions like Sonogashira and click chemistry (azide-alkyne cycloaddition). It serves as a precursor for heterocyclic compounds and is used in the development of potential drug candidates and other specialty chemicals. Due to its high reactivity, it requires careful handling. It is flammable, corrosive, and can cause severe skin burns and eye damage. It is typically stored under an inert atmosphere and at low temperatures to prevent polymerization or degradation.
    Physical Properties

    Boiling Point: 77.717 °C at 760 mmHg

    Flash Point: -2.264 °C

    Density: 0.839 g/cm3

    mg g kg ml l t