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    321574-04-3

    Catalog No. EBD2760836

    CAS 321574-04-3

    Name 2-(4-BROMO-2-METHYLPHENYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE

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    Basic Information

    Molecular Formula: C13H18BBrO2

    Molecular Weight: 297.0

    Categories: Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks

    Product Description:
    2-(4-Bromo-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a pinacol boronic ester derivative, characterized by a bromo-substituted aromatic ring. This compound serves as a versatile organoboron reagent in synthetic chemistry, primarily utilized in Suzuki-Miyaura cross-coupling reactions. The presence of both the boronic ester group and the bromine atom on the aromatic ring makes it a valuable bifunctional building block, allowing for sequential functionalization. Its primary application is as a key synthetic intermediate in the preparation of more complex organic molecules, particularly in pharmaceutical research and development. It is frequently employed in the construction of biaryl structures, which are common scaffolds in many active pharmaceutical ingredients (APIs) and drug candidates. The compound is commercially available from major chemical suppliers for use in laboratory-scale synthesis and medicinal chemistry programs.
    Physical Properties
    mg g kg ml l t