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    32683-02-6

    Catalog No. EBD2200508

    CAS 32683-02-6

    Name Ethyl aminocyanoacetate

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    Basic Information

    Synonyms: Ethylaminocyanoacetate ethyl3-nitriloalaninate Alanine,3-nitrilo-,ethylester

    Molecular Formula: C5H8N2O2

    Molecular Weight: 128.13

    Categories: Synthetic Chemistry > Organic Building Blocks > Cyano Compounds Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    Ethyl 2-amino-2-cyanoacetate is a versatile bifunctional organic building block. Its molecular structure features both a reactive amino group and a cyano group attached to the same carbon atom, which is further esterified. This unique arrangement makes it a valuable precursor in heterocyclic chemistry. The compound is primarily employed as a key intermediate in the synthesis of various nitrogen-containing heterocycles. It serves as a crucial starting material for the preparation of pyrimidine, pyrazole, and imidazole derivatives. These heterocyclic scaffolds are of significant interest in medicinal chemistry for the development of pharmaceutical agents, including potential kinase inhibitors and other bioactive molecules. Its reactivity allows for cyclocondensation reactions with various electrophiles. While its direct application is in synthetic organic chemistry as a specialized building block, the final products derived from it often target biological applications. It is commercially available from chemical suppliers specializing in fine chemicals and advanced intermediates for research and development.
    Physical Properties

    Boiling Point: 202.9 °C at 760 mmHg

    Flash Point: 76.5 °C

    Density: 1.144 g/cm3

    mg g kg ml l t