N-BOC-D-Arginine hydrochloride, CAS No. 35897-34-8

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35897-34-8

Catalog No. EBD8789

CAS 35897-34-8

Name N-BOC-D-Arginine hydrochloride

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Basic Information

Synonyms: Boc-L-Arg-OH.HCl tert-butyloxycarbonyl-arginine N~2~-(tert-butoxycarbonyl)-N~5~-(diaminomethylidene)ornithine N~2~-(tert-butoxycarbonyl)-N~5~-(diaminomethylidene)-L-ornithinehydrochloride tert-butyloxycarbonyl-argininehydrochloride Boc-Arg-OH.HCl Boc-Arg-OH·HCl Boc-L-ArginineHCL Boc-Arg-OH• HCl Boc-Arg-OH,HCl N-Boc-D-ArginineHydrochloride Boc-Arg-OHhydrochloride N-Boc-D-ArginineHyd

Molecular Formula: C11H23ClN4O4

Molecular Weight: 310.78

MDL Number: MFCD00042632

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks

Product Description:

N-BOC-D-Arginine hydrochloride is a protected derivative of the non-proteinogenic amino acid D-arginine. Its structure features a guanidino group and a tert-butoxycarbonyl (Boc) protecting group attached to the alpha-amino function, presented as the hydrochloride salt for enhanced stability and solubility. This compound is primarily utilized as a key building block in solid-phase peptide synthesis (SPPS) and solution-phase organic synthesis, enabling the incorporation of D-arginine residues into peptides and peptidomimetics. The Boc group serves as a temporary protecting group that can be selectively removed under acidic conditions, facilitating the construction of complex peptide sequences with improved metabolic stability. It is widely employed in pharmaceutical research for developing bioactive peptides, enzyme inhibitors, and therapeutic candidates targeting cardiovascular, neurological, and immunological pathways. Additionally, it serves as a standard reference material in analytical chemistry for amino acid analysis and chiral purity determination.

Physical Properties

Boiling Point: 494 °C at 760 mmHg

Flash Point: >230 °F

Density: 1.28 g/cm3

Refractivity: -8 ° (C=2, H2O)

Storage: -15°C