4-(4-Aminophenyl)morpholin-3-one, CAS No. 438056-69-0

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438056-69-0

Catalog No. EBD40900

CAS 438056-69-0

Name 4-(4-Aminophenyl)morpholin-3-one

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Basic Information

Synonyms: 4-(4-aminophenyl)morpholin-3-one 3-Morpholinone,4-(4-aminophenyl)- 4-(4-Aminophenyl)morpholin-3-on 4-(4-Aminophenyl)-morpholin-3-one 4-(4-aminophenyl)-3-Morpholinone 4-(4-Aminophlenyl)Morpholin-3-one

Molecular Formula: C10H12N2O2

Molecular Weight: 192.21

MDL Number: MFCD08236742

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

4-(4-Aminophenyl)morpholin-3-one is an organic compound featuring a morpholinone core substituted with a para-aminophenyl group. This structure combines an aromatic amine with a heterocyclic lactam, making it a versatile bifunctional building block. This compound is primarily utilized as a key pharmaceutical intermediate in medicinal chemistry research and drug development. Its structure is integral to the synthesis of various biologically active molecules, particularly those targeting protein kinases and other enzymes. It serves as a core scaffold or a precursor for constructing more complex heterocyclic systems found in potential drug candidates. As a synthetic intermediate, it is valued for its amine functionality, which allows for further derivatization through amide coupling or reductive amination, and its morpholinone ring, which can impart favorable pharmacokinetic properties. It is typically handled as a solid under standard laboratory conditions.

Physical Properties

Boiling Point: 502.3 °C at 760 mmHg

Flash Point: 257.6 °C

Density: 1.268 g/cm3