3-Hydroxytetrahydrofuran, CAS No. 453-20-3

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453-20-3

Catalog No. EBD2224251

CAS 453-20-3

Name 3-Hydroxytetrahydrofuran

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Basic Information

Synonyms: 3-Hydroxytetrahydrofuran 3-Furanol,tetrahydro- oxolan-3-ol

Molecular Formula: C4H8O2

Molecular Weight: 88.11

MDL Number: MFCD00005374

Categories: Materials Chemistry > Polymers and Macromolecular Materials > Polyester and Bio-based Polymer Precursors Synthetic Chemistry > Organic Building Blocks > Other Organic Building Blocks

Product Description:

3-Hydroxytetrahydrofuran is a heterocyclic organic compound featuring a tetrahydrofuran ring substituted with a hydroxyl group. It is a versatile chiral building block and a key monomer in polymer chemistry. Its primary industrial significance lies in its role as a precursor for the synthesis of biodegradable polymers, particularly polyesters like poly(3-hydroxybutyrate) (PHB) and its copolymers. These materials are valued for their biocompatibility and sustainability. Additionally, it serves as a crucial intermediate in the production of various pharmaceuticals, including antiviral and cardiovascular drugs, where its chiral center is essential for biological activity. As a bifunctional molecule containing both a hydroxyl group and a cyclic ether, it is also a valuable synthon in organic synthesis for constructing complex molecular architectures, especially in the preparation of other heterocycles and fine chemicals.

Physical Properties

Boiling Point: 181 °C(lit.)

Flash Point: 81 °C

Density: 1.09 g/mL at 25 °C(lit.)

Refractivity: n20/D 1.45(lit.)

Analytical Data

Appearance: light yellow liquid