L-Cyclopropylglycine, CAS No. 49606-99-7

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49606-99-7

Catalog No. EBD6879

CAS 49606-99-7

Name L-Cyclopropylglycine

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Basic Information

Synonyms: (2S)-amino(cyclopropyl)ethanoicacid (S)-2-Cyclopropylglycine (S)-Cyclopropylglycine (S)-Amino-cyclopropyl-aceticacid L-Cyclopropylglycine

Molecular Formula: C5H9NO2

Molecular Weight: 115.13

MDL Number: MFCD06659116

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

Product Description:

L-Cyclopropylglycine is a non-proteinogenic amino acid derivative characterized by a cyclopropane ring fused to the glycine backbone. It serves as a key chiral building block in medicinal chemistry and pharmaceutical research. Its primary application is as a crucial intermediate in the synthesis of various pharmaceutical agents. Notably, it is a key precursor in the production of specific antibiotics and other bioactive compounds. The rigid cyclopropane ring introduces conformational constraints, which can enhance binding affinity and metabolic stability in drug candidates targeting enzymes or receptors. This compound is also utilized in biochemical studies to investigate enzyme mechanisms and as a component in the synthesis of peptides with modified properties. It is commercially available for research purposes from suppliers specializing in fine chemicals and amino acid derivatives.

Physical Properties

Boiling Point: 253.5 °C at 760 mmHg

Flash Point: 107.1 °C

Density: 1.2 g/cm3

Storage: 2-8°C