(2,4-Dichlorophenyl)hydrazine hydrochloride, CAS No. 5446-18-4

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5446-18-4

Catalog No. EBD40746

CAS 5446-18-4

Name (2,4-Dichlorophenyl)hydrazine hydrochloride

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Basic Information

Synonyms: 2,4-Dichlorophenylhydrazinehydrochloride 4-Bromo-3-Aminoacetophdnone 2,4-Dichoropheynylhydrazinehydrochloride (2,4-Dichlorophenyl)hydrazinehydrochloride

Molecular Formula: C6H7Cl3N2

Molecular Weight: 213.49

MDL Number: MFCD00012929

Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

(2,4-Dichlorophenyl)hydrazine hydrochloride is a hydrazine derivative featuring a 2,4-dichlorophenyl group attached to a hydrazine moiety, stabilized as the hydrochloride salt. It appears as a crystalline solid and is a key building block in organic synthesis. This compound is primarily utilized as an intermediate in the pharmaceutical industry for the synthesis of heterocyclic compounds, particularly indoles, pyrazoles, and triazoles. These heterocycles are core structures in many active pharmaceutical ingredients (APIs), including anti-inflammatory, antifungal, and anticancer agents. Its role in constructing the indole ring via the Fischer indole synthesis is especially notable. As a substituted phenylhydrazine, it also serves as a versatile synthetic building block in general organic chemistry, enabling the introduction of the 2,4-dichlorophenylhydrazine moiety into target molecules. It should be handled with care due to its potential irritant and sensitizing properties.

Physical Properties

Melting Point: 220-224 °C(lit.)

Boiling Point: 268.8 °C at 760 mmHg

Flash Point: 116.4 °C

Density: 1.475 g/cm3

Solubility: soluble

Analytical Data

Appearance: white to light yellow crystal powder