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    602-00-6

    Catalog No. EBD21980

    CAS 602-00-6

    Name 3-Hydroxy-2-nitrobenzoic acid

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    Basic Information

    Synonyms: 3-Hydroxy-2-nitrobenzoicacid

    Molecular Formula: C7H5NO5

    Molecular Weight: 183.12

    MDL Number: MFCD00017003

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters

    Product Description:
    3-Hydroxy-2-nitrobenzoic acid is an aromatic compound featuring both a carboxylic acid and a nitro group ortho to a phenolic hydroxyl group. This specific substitution pattern makes it a versatile bifunctional building block in organic synthesis. Its primary application is as a key pharmaceutical intermediate. It serves as a crucial precursor in the synthesis of various bioactive molecules, including certain quinolone antibiotics. The presence of multiple reactive sites allows for selective functionalization, enabling the construction of complex heterocyclic systems common in drug discovery. As a specialty chemical, it is utilized in research and development for constructing molecular libraries and exploring structure-activity relationships. It is commercially available for laboratory use and requires standard safety precautions for handling nitroaromatic and acidic compounds.
    Physical Properties

    Melting Point: 179-181°C

    Boiling Point: 363°C

    Flash Point: 167°C

    Density: 1.631

    Analytical Data

    Appearance: white to light yellow crystal powder

    mg g kg ml l t