6 - Chloropyridine - 2 - boronic acid pinacol ester, CAS No. 652148-92-0

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

652148-92-0

Catalog No. EBD43240

CAS 652148-92-0

Name 6 - Chloropyridine - 2 - boronic acid pinacol ester

Get Quote

Basic Information

Synonyms: 6-Chloropyridine-2-boronicacidpinacolester 2-chloro-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 2-Chloro-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine 2-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine pyridine,2-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

Molecular Formula: C11H15BClNO2

Molecular Weight: 239.51

Categories: Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

Product Description:

6-Chloropyridin-2-ylboronic acid pinacol ester is an organoboron compound featuring a pyridine ring substituted with a chlorine atom at the 6-position and a boronic acid pinacol ester group at the 2-position. This structure makes it a versatile and valuable synthetic building block, particularly in cross-coupling reactions such as the Suzuki-Miyaura reaction. Its primary application is as a key intermediate in pharmaceutical research and development. The chloropyridine-boronate moiety is a privileged scaffold used to construct more complex heterocyclic systems found in active pharmaceutical ingredients (APIs) and drug candidates. It is frequently employed in the synthesis of compounds targeting various therapeutic areas. As a bench-stable solid, it offers advantages in handling and storage compared to some boronic acids. Standard safety precautions for handling laboratory chemicals should be observed.

Physical Properties

Boiling Point: 338.2 °C at 760 mmHg

Flash Point: 158.3 °C

Density: 1.14 g/cm3