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    6554-61-6

    Catalog No. EBD13672

    CAS 6554-61-6

    Name 4,5-dichloropyrimidine

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    Basic Information

    Synonyms: Pyrimidine,4,5-dichloro- 4,5-Dichloropyrimidine

    Molecular Formula: C4H2Cl2N2

    Molecular Weight: 148.98

    MDL Number: MFCD09743880

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    4,5-Dichloropyrimidine is a halogenated heterocyclic compound featuring a pyrimidine ring substituted with chlorine atoms at the 4 and 5 positions. It serves as a versatile and valuable building block in organic synthesis, particularly in medicinal chemistry. Its primary application is as a key intermediate in the synthesis of various pharmaceutical compounds. The chlorine atoms are reactive sites that can undergo nucleophilic aromatic substitution reactions, allowing for the introduction of diverse functional groups such as amines, alkoxides, and thiols. This makes it a crucial precursor for constructing complex molecules, including nucleoside analogs and other biologically active heterocycles. Due to its reactivity and utility in constructing drug-like scaffolds, it is widely used in research and development for creating potential therapeutic agents. As a halogenated pyrimidine, it requires careful handling under standard laboratory safety protocols.
    Physical Properties

    Boiling Point: 219.727 °C at 760 mmHg

    Flash Point: 107.572 °C

    Density: 1.493 g/cm3

    mg g kg ml l t