Ethylenebis(oxyethylenenitrilo)tetraacetic acid, CAS No. 67-42-5

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67-42-5

Catalog No. EBD15738

CAS 67-42-5

Name Ethylenebis(oxyethylenenitrilo)tetraacetic acid

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Basic Information

Synonyms: 6,9-Dioxa-3,12-diazatetradecanedioicacid,3,12-bis(carboxymethyl)- 3,12-bis(carboxylatomethyl)-6,9-dioxa-3,12-diazoniatetradecane-1,14-dioate Ethyleneglycol-bis-(2-aminoethyl)tetraaceticacid EGTA 1,2-Di(2-aminoethoxy)ethane-N,N,N,N-tetraaceticacid Ethyleneglycolbis(aminoethylether)-tetra-aceticacid Egtazicacid Ethylenebis(oxyethylenenitrilo)tetraaceticacid 3,12-Bis(carboxymethyl)-6,9-dioxa-3,12-diazatetradecane-1,14-dioicacid GEDTA

Molecular Formula: C14H24N2O10

Molecular Weight: 380.35

MDL Number: MFCD00004291

Categories: Medicinal Chemistry > Pharmaceutical Excipients > Isotonic Agents, pH Adjusters, and Buffers

Product Description:

Ethylenebis(oxyethylenenitrilo)tetraacetic acid (EGTA, CAS 67-42-5) is a chelating agent structurally related to EDTA, featuring an ether oxygen bridge between two iminodiacetic acid moieties. Its primary application is in biochemical and life science research as a selective calcium ion (Ca__) chelator, with a significantly higher affinity for Ca__ over magnesium ions (Mg__), making it a standard tool for studying calcium-dependent cellular processes, enzyme kinetics, and signal transduction pathways. In analytical chemistry, EGTA serves as a specialized reagent for complexometric titrations and metal ion buffering, particularly in systems requiring precise control of calcium concentration.

Physical Properties

Melting Point: 241 °C (dec.)(lit.)

Boiling Point: 678.016 °C at 760 mmHg

Flash Point: 363.851 °C

Density: 1.433 g/cm3

Solubility: 1

Storage: Store at RT.

Analytical Data

Appearance: white to slightly off-white powder