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    6968-76-9

    Catalog No. EBD37871

    CAS 6968-76-9

    Name 1-(3-Methoxyphenyl)piperazine dihydrochloride

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    Basic Information

    Synonyms: 1-(3-methoxyphenyl)piperazinehcl 4-(3-methoxyphenyl)piperazin-1-ium 1-(3-methoxyphenyl)piperazinehydrochloride 1-(3-Methoxyphenyl)piperazinedihydrochloride n-(3-methoxyphenyl)piperazine 1-(3-m-methoxyphenyl)piperazine 1-(3-methoxylphenyl)piperazine 1-(3-methyoxyphenyl)-piperazine

    Molecular Formula: C11H18Cl2N2O

    Molecular Weight: 265.18

    MDL Number: MFCD00035285

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    1-(3-Methoxyphenyl)piperazine dihydrochloride is a white to off-white crystalline powder. It is a piperazine derivative substituted with a 3-methoxyphenyl group at the nitrogen atom, and is commonly supplied as its stable dihydrochloride salt. This compound is a key pharmaceutical intermediate and a versatile chemical building block. Its primary application is in the synthesis of various biologically active molecules, particularly in medicinal chemistry research. It serves as a crucial precursor for the development of compounds targeting the central nervous system, including potential antipsychotic and antidepressant agents, due to its structural similarity to known pharmacophores that interact with serotonin and dopamine receptors. As a substituted piperazine, it is a valuable amine synthon in organic synthesis. The compound should be stored in a cool, dry place, and handled with appropriate personal protective equipment as it may cause irritation to the skin, eyes, and respiratory system.
    Physical Properties

    Melting Point: 201-204 °C

    mg g kg ml l t