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    701261-35-0

    Catalog No. EBD3070321

    CAS 701261-35-0

    Name 2,2-dimethylpropylboronic acid

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    Basic Information

    Synonyms: NEOPENTYLBORONICACI NEOPENTYLBORONICACID 2,2-DIMETHYLPROPYLBORONICACID BORONICACID,(2,2-DIMETHYLPROPYL)-(9CI) NEOPENTYLBORONICACID/2,2-DIMETHYLPROPYLBORONICACID (2,2-dimethylpropyl)boronicacid

    Molecular Formula: C5H13BO2

    Molecular Weight: 115.97

    Categories: Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters Synthetic Chemistry > Catalysts and Ligands > Other Catalysts and Ligands

    Product Description:
    2,2-Dimethylpropylboronic acid is an organoboron compound characterized by a neopentyl (2,2-dimethylpropyl) group attached to a boronic acid functional group. This structure imparts significant steric hindrance around the boron center, which is a key feature influencing its reactivity and stability. Its primary application is in organic synthesis, particularly in transition-metal-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction. The sterically hindered neopentyl group can modulate the reactivity of the boronic acid, potentially leading to improved selectivity or stability in certain coupling processes. It serves as a valuable synthetic building block for introducing the bulky neopentyl moiety into more complex molecules. Additionally, organoboron compounds like this can act as ligands or precursors in catalysis. As a boronic acid, it requires careful handling under inert atmosphere (e.g., nitrogen or argon) to prevent protodeboronation or oxidation. It is typically stored at low temperatures (e.g., 2-8°C) to maintain stability.
    Physical Properties

    Melting Point: 85-89 °C

    Boiling Point: 191.7°C at 760 mmHg

    Flash Point: 69.7°C

    Density: 0.905g/cm3

    Storage: 2-8°C

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