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    74204-00-5

    Catalog No. EBD35019

    CAS 74204-00-5

    Name 3-bromo-5-methylphenol

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    Basic Information

    Synonyms: 5-Bromo-m-cresol 74204-00-5 phenol,3-bromo-5-methyl- 3-bromo-5-methylphenol

    Molecular Formula: C7H7BrO

    Molecular Weight: 187.03

    Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Phenols and Ethers

    Product Description:
    3-Bromo-5-methylphenol is an organic compound featuring a phenol ring substituted with a bromine atom at the 3-position and a methyl group at the 5-position. It is a solid at room temperature and serves as a versatile bifunctional building block in organic synthesis, combining the reactivity of a phenol and an aryl bromide. Its primary application is in chemical research and development as a key synthetic intermediate. The phenolic hydroxyl group can undergo etherification, esterification, or serve as a directing group in metal-catalyzed cross-coupling reactions. The aryl bromide moiety is highly reactive in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) for constructing complex biaryl or conjugated systems. This makes it valuable for synthesizing ligands, pharmaceutical intermediates, and materials science precursors. As a halogenated phenol, it requires careful handling due to potential skin and eye irritation. It is typically used in controlled laboratory environments for constructing more complex molecular architectures rather than having a direct, standalone industrial application as an API, agrochemical, or functional material.
    Physical Properties

    Melting Point: 61-62 °C

    Boiling Point: 249.329 °C at 760 mmHg

    Flash Point: 104.59 °C

    Density: 1.554 g/cm3

    mg g kg ml l t