(-)-2-Amino-4-phenylbutyric acid, CAS No. 82795-51-5

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82795-51-5

Catalog No. EBD7244

CAS 82795-51-5

Name (-)-2-Amino-4-phenylbutyric acid

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Basic Information

Synonyms: D-Homophenylalanine (R)-2-Amino-4-phenylbutanoicacid (2R)-2-ammonio-4-phenylbutanoate (R)-2-Amino-4-phenylbutyricacid H-D-HoPhe-OH d-homophe d-homophenyl-ala d-(-)-homophenylalanine dhpa d-2-amino-4-phenylbutyricacid d-alpha-amino-4-phenylbutyricacid homo-d-phenylalanine (R)-alpha-Amino-benzenebutanoicacid (-)-2-Amino-4-phenylbutyricacid

Molecular Formula: C10H13NO2

Molecular Weight: 179.22

MDL Number: MFCD00063091

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

Product Description:

D-Phenylalanine, also known as (R)-2-Amino-3-phenylpropanoic acid, is a non-proteinogenic D-amino acid derivative. It is the enantiomer of the naturally occurring L-phenylalanine. Structurally, it features a phenyl group attached to the beta-carbon of an alanine backbone, with the D-configuration at the chiral center. Its primary application is as a chiral building block in pharmaceutical synthesis. It serves as a key intermediate for the production of various peptide-based drugs and enzyme inhibitors where the D-configuration is crucial for biological activity, metabolic stability, or specific receptor binding. For instance, it is used in the synthesis of certain ACE inhibitors and other bioactive peptides. As a non-natural amino acid, it is also utilized in biochemical and life science research for studying enzyme specificity, peptide structure-activity relationships, and as a component in custom peptide synthesis. It is commercially available for these purposes from suppliers of fine chemicals and biochemicals.

Physical Properties

Melting Point: >300 °C(lit.)

Boiling Point: 324.8 °C at 760 mmHg

Flash Point: 150.2 °C

Density: 1.164 g/cm3

Refractivity: -45 ° (C=1, 3mol/L HCl)

Storage: Store at RT.

Analytical Data

Appearance: Beige powder