rotenone, CAS No. 83-79-4

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

83-79-4

Catalog No. EBD2205139

CAS 83-79-4

Name rotenone

Get Quote

Basic Information

Synonyms: 2-Isopropenyl-8,9-dimethoxy-1,2,12,12a-tetrahydro-6aH-chromeno[3,4-b]furo[2,3-h]chromen-6-on rotenone (2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9-dimethoxychromeno(3,4-b)furo(2,3-h)chromen-6-one tubatoxin 8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one (2R,6aS,12aR)-8,9-dimethoxy-2-(1-methylethenyl)-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one

Molecular Formula: C23H22O6

Molecular Weight: 394.42

Categories: Agrochemicals > Pesticide Chemistry > Insecticides

Product Description:

Rotenone is a naturally occurring isoflavone compound extracted primarily from the roots of plants belonging to the *Derris*, *Lonchocarpus*, and *Tephrosia* genera. It is a crystalline solid with the molecular formula C₂₃H₂₂O₆ and is known for its high lipophilicity. Its primary and most significant application is as a broad-spectrum insecticide and piscicide (fish toxicant). Rotenone acts as a potent mitochondrial complex I inhibitor, disrupting cellular respiration and ATP production, leading to rapid paralysis and death in target organisms. Historically and in some current niche applications, it has been used in organic farming, aquaculture management (to remove unwanted fish species), and household pest control. Due to its high toxicity to fish and potential ecological impact, its use is heavily regulated or banned in many countries. It is also a valuable tool in neuroscience research for inducing Parkinson's disease models in laboratory animals by selectively destroying dopaminergic neurons.

Physical Properties

Melting Point: 159-164 °C(lit.)

Boiling Point: 210-220 °C/0.5 mmHg(lit.)

Flash Point: 244.6 °C

Density: 1.271 g/cm3

Solubility: 0.2 mg/L at 20 °C in water

Safety Information

Packing Level: III

Hazard Category: 6.1

Transport Codes: 2811

Analytical Data

Appearance: white or off-white powder