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    869973-96-6

    Catalog No. EBD2222592

    CAS 869973-96-6

    Name (1-Methyl-1H-pyrazol-3-yl)boronic acid

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    Basic Information

    Synonyms: (1-Methyl-1H-pyrazol-3-yl)boronicacid Boronicacid,(1-methyl-1H-pyrazol-3-yl)-

    Molecular Formula: C4H7BN2O2

    Molecular Weight: 125.92

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters

    Product Description:
    N-Methyl-3-pyrazoleboronic acid is a heterocyclic boronic acid derivative. It features a pyrazole ring substituted with a methyl group on the nitrogen atom and a boronic acid group at the 3-position. This compound is a versatile synthetic building block, primarily valued for its role in Suzuki-Miyaura cross-coupling reactions, a key method for forming carbon-carbon bonds. Its primary application is in medicinal chemistry and pharmaceutical research as a crucial intermediate. The pyrazole scaffold is a privileged structure in drug discovery, and this specific boronic acid is used to incorporate the N-methylpyrazole moiety into larger, more complex molecules. It is instrumental in the synthesis of various biologically active compounds and potential drug candidates, particularly those targeting kinases and other enzymes. As a boronic acid, it requires careful handling under inert atmosphere (e.g., nitrogen or argon) to prevent protodeboronation and maintain stability. It is typically stored at low temperatures (2-8°C or -20°C) to prolong its shelf life. Its utility spans from early-stage research to the development of active pharmaceutical ingredients (APIs).
    Physical Properties
    mg g kg ml l t