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    885267-36-7

    Catalog No. EBD30806

    CAS 885267-36-7

    Name 6-Bromo-3-fluoropicolinaldehyde

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    Basic Information

    Synonyms: 6-bromo-3-fluoropyridine-2-carbaldehyde 3-fluoro-6-bromo-2-pyridinecarboxaldehyde 6-bromo-3-fluoropyridine-2-carboxaldehyde 6-bromo-3-fluoropyridine-2-carboxaldehyde98% 6-bromo-3-fluoro-2-formylpyridine,6-bromo-3-fluoropicolinaldehyde 6-bromo-3-fluoro-pyridine-2-carbaldehyde 6-Bromo-3-fluoropicolinaldehyde

    Molecular Formula: C6H3BrFNO

    Molecular Weight: 204.0

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    6-Bromo-3-fluoro-2-pyridinecarboxaldehyde is a halogenated heterocyclic building block featuring both bromine and fluorine substituents on a pyridine ring, along with an aldehyde functional group. This specific substitution pattern makes it a valuable and versatile intermediate in synthetic organic chemistry. Its primary application is in the pharmaceutical industry as a key intermediate for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. The presence of reactive sites (bromine for cross-coupling reactions and aldehyde for condensation or reduction) allows for efficient structural diversification. It is notably used in the development of kinase inhibitors and other biologically active small molecules targeting various therapeutic areas. As a bifunctionalized pyridine derivative, it serves as a crucial precursor for constructing more complex heterocyclic scaffolds. Its utility extends beyond pharmaceuticals into materials science and agrochemical research, where fluorinated and brominated pyridines are often sought for their unique electronic and physicochemical properties.
    Physical Properties

    Boiling Point: 228.573°C at 760 mmHg

    Flash Point: 92.038°C

    Density: 1.778g/cm3

    mg g kg ml l t