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    891785-28-7

    Catalog No. EBD1616434

    CAS 891785-28-7

    Name 6-bromoisoquinolin-3-amine

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    Basic Information

    Synonyms: 3-amino-6-bromoisoquinoline 6-bromo-3-isoquinolinamine 6-bromoisoquinolin-3-amine,3-amino-6-bromo-2-azanaphthalene

    Molecular Formula: C9H7BrN2

    Molecular Weight: 223.07

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    6-Bromoisoquinolin-3-amine is an organic compound featuring a fused isoquinoline ring system substituted with a bromine atom at the 6-position and an amino group at the 3-position. This structure makes it a versatile heterocyclic building block, particularly valuable in medicinal chemistry. Its primary application is as a key synthetic intermediate in pharmaceutical research and development. The presence of both a reactive bromine atom (suitable for cross-coupling reactions like Suzuki or Buchwald-Hartwig amination) and an amino group (which can be further functionalized) allows for the efficient construction of complex molecules. It is notably used in the synthesis of compounds targeting various biological pathways, including kinase inhibitors and other potential therapeutic agents. As a bifunctional heterocyclic amine, it serves as a fundamental scaffold in organic synthesis. Its utility extends beyond specific drug candidates, making it a common starting material for constructing diverse chemical libraries in drug discovery programs.
    Physical Properties

    Boiling Point: 387.6 °C at 760 mmHg

    Flash Point: 188.2 °C

    Density: 1.649 g/cm3

    mg g kg ml l t