Tetrahydro-furan-3-carboxylic acid, CAS No. 89364-31-8

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89364-31-8

Catalog No. EBD2000

CAS 89364-31-8

Name Tetrahydro-furan-3-carboxylic acid

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Basic Information

Synonyms: tetrahydrofuran-3-carboxylicacid 3-Furancarboxylicacid,tetrahydro- Oxolane-3-CarboxylicAcid Tetrahydro-furan-3-carboxylicacid tetrahydro-3-furancarboxylicacid tetrahydro-3-furoicacid rarechemalbe0888 3-tetrahydrofuroic 3-furancarboxylicacid,tetrahydro-(9ci) tetrahydro-3-furoicacid,99%

Molecular Formula: C5H8O3

Molecular Weight: 116.12

MDL Number: MFCD00075173

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters

Product Description:

Tetrahydrofuran-3-carboxylic acid is a heterocyclic carboxylic acid featuring a tetrahydrofuran ring. It serves as a versatile chiral building block in organic synthesis, particularly valued for its rigid, oxygen-containing heterocyclic structure and the presence of a carboxylic acid functional group, which allows for further derivatization. Its primary application is in the pharmaceutical industry as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). For instance, it is a crucial precursor in the production of certain antiviral drugs and other therapeutic agents where the tetrahydrofuran moiety is a core structural element. The compound's chirality also makes it relevant for the synthesis of enantiomerically pure drugs. As a bifunctional molecule, it is widely used in medicinal chemistry research for constructing complex molecular architectures. It is commercially available from suppliers specializing in fine chemicals and pharmaceutical intermediates.

Physical Properties

Boiling Point: 140 °C/15 mmHg(lit.)

Flash Point: >110 °C

Density: 1.214 g/mL at 25 °C(lit.)

Refractivity: n20/D 1.4605(lit.)