Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    899436-71-6

    Catalog No. EBD6283

    CAS 899436-71-6

    Name 2-methylpyridine-3-boronic acid

    Get Quote
    Basic Information

    Synonyms: 2-methylpyridine-3-boronicacid 2-picoline-3-boronicacid 2-methyl-3-pyridinylboronicacid 2-methyl-3-pyridineboronicacid 2-methylpyridine-3-boronicacid96% 2-methylpyridin-3-ylboronicacid refdupl:2-methylpyridine-3-boronicacid 3-borono-2-methylpyridine

    Molecular Formula: C6H8BNO2

    Molecular Weight: 136.94

    MDL Number: MFCD07368825

    Categories: Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    2-Methylpyridine-3-boronic acid is an organoboron compound featuring a boronic acid functional group attached to the 3-position of a 2-methylpyridine (2-picoline) ring. This structure classifies it as a heteroarylboronic acid, a valuable class of reagents in synthetic chemistry. Its primary application is as a versatile building block in cross-coupling reactions, most notably the Suzuki-Miyaura reaction. The boronic acid group enables efficient carbon-carbon bond formation with various aryl or heteroaryl halides under palladium catalysis. The presence of the pyridine ring and the methyl substituent makes it a useful precursor for constructing more complex molecules containing substituted pyridine motifs. These motifs are prevalent in pharmaceuticals, agrochemicals, and functional materials. Consequently, this compound is frequently employed in medicinal chemistry research for the synthesis of drug candidates and intermediates. As a solid, it requires storage under inert conditions to prevent protodeboronation or oxidation. It is a standard reagent offered by numerous fine chemical and building block suppliers for research and development purposes.
    Physical Properties

    Boiling Point: 303.6 °C at 760 mmHg

    Flash Point: 137.4 °C

    Density: 1.18 g/cm3

    mg g kg ml l t