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    928783-85-1

    Catalog No. EBD35618

    CAS 928783-85-1

    Name 1-bromo-3-chloro-5-(trifluoromethyl)benzene

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    Basic Information

    Synonyms: 1-Bromo-3-chloro-5-(trifluoromethyl)benzene Benzene,1-bromo-3-chloro-5-(trifluoromethyl)- 3-Bromo-5-Chlorobenzotrifluoride 3-chloro-5-trifluoromethylbromobenzene 1-bromo-3-chloro-5-(trifluoromethyl)benzene,3-bromo-5-chloro-alpha,alpha,alpha-trifluorotoluene 3-bromo-5-chlorobenzotrifluoride,97%+

    Molecular Formula: C7H3BrClF3

    Molecular Weight: 259.45

    Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    1-Bromo-3-chloro-5-(trifluoromethyl)benzene is a halogenated aromatic compound featuring a benzene ring substituted with bromine, chlorine, and a trifluoromethyl group at the 1, 3, and 5 positions, respectively. This molecular structure combines multiple reactive sites, making it a versatile building block in organic synthesis. Primarily, this compound serves as a key intermediate in the pharmaceutical and agrochemical industries. The bromine and chlorine atoms allow for selective cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), while the trifluoromethyl group enhances metabolic stability and lipophilicity in drug candidates. It is commonly used to construct complex molecules for medicinal chemistry programs, particularly in the development of kinase inhibitors and other therapeutic agents. Additionally, its electron-deficient aromatic ring makes it suitable for nucleophilic aromatic substitution reactions. Due to its high reactivity and structural specificity, it is also employed in the synthesis of advanced materials and specialty chemicals. Proper handling is required as it may cause skin and eye irritation.
    Physical Properties
    mg g kg ml l t