3-Fluoro-4-(4-morpholinyl)-benzeamine, CAS No. 93246-53-8

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93246-53-8

Catalog No. EBD42175

CAS 93246-53-8

Name 3-Fluoro-4-(4-morpholinyl)-benzeamine

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Basic Information

Synonyms: akosb033533 3-fluoro-4-(4-morpholinyl)-benzenamine 3-fluoro-4-morpholin-4-yl-phenylamine 3-fluoro-4-morpholin-aniline 3-fluoro-4-morpholinoaniline 3-fluoro-4-morpholinophenylamine timtec-bbsbb010944 3-Fluoro-4-(4-Morpholinyl)-Benzeamine 3-Fluoro-4-morpholinylaniline 3-fluoro-4-(morpholin-4-yl)aniline 3-Fluoro-4-(4-morpholinyl)-aniline 3-fluoro-4-morpholin--4-yl-phenylamine 3-Fluoro-4-(4-Morpholinyl)Benzeamine

Molecular Formula: C10H13FN2O

Molecular Weight: 196.22

MDL Number: MFCD02571270

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

3-Fluoro-4-(4-morpholinyl)aniline is an organic compound featuring a benzene ring substituted with an amino group, a fluorine atom, and a morpholine moiety. It is a solid with a molecular formula of C10H13FN2O and a molecular weight of 196.22 g/mol. The presence of both an aromatic amine and a morpholine ring makes it a versatile building block. This compound is primarily used as a key pharmaceutical intermediate in medicinal chemistry research and drug development. Its structure is a common motif found in the synthesis of various biologically active molecules, particularly kinase inhibitors. For instance, it serves as a crucial precursor in the synthesis of potent and selective inhibitors targeting specific kinases involved in cancer and inflammatory diseases. As an aniline derivative, it is a reactive amine suitable for further functionalization, such as amide bond formation or reductive amination. Standard safety precautions for handling amines should be observed, including the use of personal protective equipment due to potential skin and eye irritation.

Physical Properties

Melting Point: 121-123 °C

Boiling Point: 364.9 °C at 760 mmHg

Flash Point: 174.5 °C

Density: 1.232 g/cm3

Analytical Data

Appearance: brown solid