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    88491-61-6

    Catalog No. EBD35463

    CAS 88491-61-6

    Name 3-Bromo-pyridazine

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    Basic Information

    Synonyms: pyridazine,3-bromo-(9ci) 3-bromopyridazine 3-bromopyridazine,97% pyridazine,3-bromo- 3-bromopyridazinehydrobromide 3-Bromo-pyridazine

    Molecular Formula: C4H3BrN2

    Molecular Weight: 158.98

    MDL Number: MFCD10688587

    Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    3-Bromopyridazine is a halogenated heterocyclic compound featuring a pyridazine ring substituted with a bromine atom at the 3-position. It serves as a versatile and valuable synthetic building block in organic chemistry. The bromine atom provides a reactive site for various cross-coupling reactions, such as Suzuki, Stille, and Buchwald-Hartwig couplings, enabling the introduction of diverse functional groups and the construction of more complex molecular architectures. Its primary application lies in pharmaceutical research and development, where it is used as a key intermediate for the synthesis of biologically active molecules. The pyridazine core is a privileged scaffold found in numerous drug candidates and agrochemicals. Specifically, 3-bromopyridazine is utilized in the preparation of compounds with potential therapeutic activities, including kinase inhibitors and other enzyme modulators. It is a fundamental starting material for constructing fused heterocyclic systems and functionalized pyridazine derivatives.
    Physical Properties

    Boiling Point: 269.972 °C at 760 mmHg

    Flash Point: 117.075 °C

    Density: 1.727 g/cm3

    mg g kg ml l t